Particulate matter exposure and risk of psoriasis

[Fred]

A Korean nationwide cohort study looking at particulate matter (PM) and onset and exacerbation of psoriasis.

Quote:

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Psoriasis is a chronic inflammatory skin disease influenced by environmental factors, including air pollution. However, large-scale evidence from Asian populations, where particulate matter (PM) exposure is relatively high, remains limited.

This study aimed to evaluate the association between long-term PM exposure and psoriasis incidence, and short-term exposure with exacerbation risk. We conducted a cohort study using the Korean National Health Insurance Service database, involving 8 396 764 individuals.

Long-term exposure was assessed based on annual average concentrations of fine PM (PM2.5) and coarse PM (PM10), while short-term exposure was measured using daily PM levels matched with control days. Long-term exposure to PM2.5 and PM10 was associated with a 19% and 27% higher risk of incident psoriasis (adjusted HR 1.19 and 1.27; 95% CI 1.16–1.22 and 1.25–1.30). Short-term exposure was linked to an increased risk of psoriasis exacerbation (adjusted OR 1.03 for PM2.5, 95% CI 1.00–1.06; adjusted OR 1.01 for PM10, 95% CI 1.00–1.03).

Stronger associations were observed in younger individuals, urban residents, those with lower socioeconomic status, ever-smokers, and patients with comorbid allergic diseases.

These findings suggest that both long-term and short-term PM exposure contribute to psoriasis onset and exacerbation, underscoring air pollution as an important modifiable risk factor in psoriasis development and control.

Source: onlinelibrary.wiley.com

*Funding: National Institute of Health

[Caroline]

Now I think that a lof of PM is bad anyhow… for any person and for all types of diseases.

[Waine]

This reminds me of the Korean version of the TV Series Designated Survivor, which had a lot of focus on air quality 

Also who would have guessed Air Pollution = Bad?!. I wonder how much they spent on this study?

[Caroline]

This reminds me of the Korean version of the TV Series Designated Survivor, which had a lot of focus on air quality 

Also who would have guessed Air Pollution = Bad?!. I wonder how much they spent on this study?

Good point.. the costs of these studies that prove the obvious. But still as everything in the medical world is currently only true if it is “Evidence Based”, it seems ok to do these studies.

I do, by accident, know that we have a Professor over here in NL, who is specialised in PM….

[mataribot]

I’m not a fan of meta studies - just wasting money unless it’s being used as rationale for a real one.

[Fred]

I’m not a fan of meta studies - just wasting money unless it’s being used as rationale for a real one.

Yep got to agree with that.

[Caroline]

I’m not a fan of meta studies - just wasting money unless it’s being used as rationale for a real one.

Yep got to agree with that.

From the point of common sense, I certainly also agree with that.


From the stubborn point of view of modern medicine… True = Evidence based… even this study has its purpose.